With creative choice of substrate analogues, Rick Sayler (@RicktheSayler) was able to trap the hottest reactive intermediate in radical SAM chemistry. Read about it in ACS Central Science.
Caught in the Act! The Adenosyl Radical.
Actinide Covalency
Some beautiful spectroscopy by Guodong Rao to probe metal-metal bonding in actinide-containing complexes. Now in Inorganic Chemistry.
COY chamber is here!
Our glove box arrived and was installed on Monday. Everything is working great. Now it’s time to make some FeS proteins!
Structure of Radical Intermediate in Biotin Biosynthesis
A project many years in the making. Very elegant spectroscopy by Dr. Lizhi Tao to divine the geometric structure of this intermediate. Beautiful biosynthetic approach to install magnetic isotopes by Dr. Corey Fugate.
Radical Intermediate Caught During B12 Biosynthesis
I’m proud of this work in JACS with Derek Gagnon illustrating the strong collaboration between the Begley and Britt labs.
I’m new here
I’m excited to have the privilege of joining the Department of Chemistry at Wake Forest University and to be part of this grand innovative idea that is Wake Downtown.
